NDS may stand for:

• Low German (Dutch: Nedersaksisch, German: Niederdeutsche Sprache, ISO 639-2 language code: nds), a West Germanic language native to Northern Germany, Denmark and the Netherlands
• Lower Saxony (German: Niedersachsen), a federal state of Germany
• NDS Group, a company specializing in television technology, including digital rights management, renamed Cisco Videoscape after its acquisition
  • NDS is also used as shorthand for VideoGuard, the encryption system created by NDS Group
• National Directorate of Security, the primary foreign and domestic intelligence agency of Afghanistan
• Nintendo DS, a 2004 portable game system
• Novell Directory Services, former name for NetIQ eDirectory, directory service software for a network
• New Data Seal, a block cipher encryption algorithm that was designed at IBM in 1975
• News Distribution Service, operated by the UK government's Central Office of Information
• Nouvelle Démocratie Sociale, a political party in Burkina Faso known in English as New Social Democracy
• Navigation Data Standard, a format for automotive-grade navigation databases
• New Democratic Party (Serbian: Нова демократска странка, Nova demokratska stranka), temporarily in 2014 the name for the Serbian political party Social Democratic Party (Serbia) (Социјалдемократска странка, Socijaldemokratska stranka, SDS)
• Nick Dal Santo (born 1984), Australian Rules footballer
• NASA Docking System, a spacecraft docking and berthing mechanism being developed for future US human spaceflight vehicles
• National Defense Strategy of the United States Secretary of Defense
• Norra Djurgårdsstaden, a neighborhood in Stockholm